Most Home Depot's and Lowes carry acrylic sheets in varying sizes up to 8'x4' up to 1/4" thick. You shouldnt need more than that for a sump unless you're building a 60+ Gal sump. If you build it more than 18" Deep front to back, you may need to install a cross brace or two to prevent bowing. Acrylic is quite easy to work with, just get some good Weld-on #16 for a nice tight seal. another shortcut to doing acrylic if you cannot find Weld-on that specifically says acrylic(NOT PVC) is to buy some strait up Acetone also available at lowes/home depot in the paint thinner section. Put 1/2 cup of acetone into a glass jar(make sure it has a tight lid with it) with some chips and or fragments of acrylic left over from your cut out. The acrylic will desolve into the acetone. Add a little bit of acrylic at a time, give it a couple hours to desolve and stir. When you get it thick as you want it, apply with a paint brush. Make sure construction takes place in a well ventelated are without sparks/ignition source, acetone is flameable. Once applied, the acetone will evaporate out, and what you will be left with is acrylic. The acetone in the mixture will also "melt" the edges of your panels slighlty, so when it dries(24+ Hours for full hardness) you are left with seals of pure acrylic
Note for those with arylic tanks. The above acetone+acrylic mixture works very very well at filling in deep gouges. It just req alot of sanding/polishing, but its imho better than having to alter the thickness of a 2' section of aquarium to sand/buff/polish out a deep gouge. Just make sure you use it while the aquarium is empty. While applying, the acetone in the mixture can weaken the pane enough that cracking can happen if the tank is full.