Phosguard absorbs phosphates, and biopellets are essentially porous media to grow bacteria, just as your liverock and existing filter does, to reduce nitrates.
That said, for tanks packed with live rock, biopellets are useless, but for smaller aquariums BC29 and under, it could prove beneficial.
They serve two different purposes and work in two different ways on two different time scales, phosguard is good for about 4 days before it saturates with phosphates, and biopellets are designed to be left in long term. Biopellets won't do any good for you in 4 days.
Hope that helps?
Jeff