A water change will help - but the best thing to do is figure out why your levels are so high and fix the problem. If your bioload is to high - you might want to think about either going bigger

or sending someone back to the lfs - or find someone to adopt one of your fish...
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Steph
300 gallon dt, 90 gallon fuge, 35 gallon fuge, 35 gallon sump, 4 Ecotech Vortechs, T-5 lights